ʻO ka Paclitaxel kahi mea i lawe ʻia mai ka yew, hiki ke hoʻopaʻa pono i ka maʻi kanesa a he lāʻau lapaʻau hōʻailona hoʻohana nui ia i ka honua. ʻO ka noiʻi lapaʻau, ʻo ka paclitaxel injection mua "Taxol" i hoʻokumu ʻia ma 1992. A hiki i kēia manawa,paclitaxelʻO ia kekahi o nā lāʻau anti-tumor botanical kaulana me ka maikaʻi maikaʻi. Loaʻa iā ia nā ʻano o ka hana kiʻekiʻe, haʻahaʻa haʻahaʻa a me ka laulā ākea. ka ma'i 'a'ai a me ka ma'i 'a'ai kala.
Hōʻike nā hopena o nā hoʻokolohua lapaʻau, i kēia manawa, ka loaʻa ʻana onā API paclitaxelʻO nā mea noiʻi ʻepekema e hōʻiliʻili i nā lālā a me nā lau o Taxus chinensis chinensis, hoʻohana i ka solvent extraction, solid phase extraction, Supercritical fluid extraction, membrane separation, chromatographic separation a me nā ʻano hana ʻē aʻe i ka hoʻokaʻawale ʻana a me nā ala ʻē aʻe. e unuhi i nā precursors e like me ke ʻano o ka paclitaxel, e like me ka bacatine III, 10 deacetyl bacatine III, etc., a laila e loaʻa i nā lāʻau lapaʻau nui paclitaxel ma o ka hoʻololi kemika o nā ʻano hana nui.
Wahi a nā helu ʻepekema, pono nā mea maʻi maʻi maʻi e ʻai ma mua o 2 grams opaclitaxeli hoʻokahi papa o ka mālama ʻana. Pono e unuhi ʻia kēia mau ʻāpana o ka paclitaxel mai ka ʻili o 4-8 mau lāʻau hihiu ʻo Taxus chinensis i ulu aʻe ma mua o 50 mau makahiki. ʻO ka lima ʻē aʻe, aia kahi koi olakino nui, e alakaʻi ana i ke kumu kūʻai kiʻekiʻe o Taxus chinensis raw material i ka makahiki holoʻokoʻa, a hāʻule ka lako i ka noi.
Wehewehe: ʻO ka pono kūpono a me nā noi i ʻōlelo ʻia ma kēia ʻatikala mai nā palapala i loaʻa i ka lehulehu.
Heluhelu lōʻihi: ʻO Yunnan Hande Bio-tech ka mea nui i ka unuhi ʻana a me ka hoʻomohala ʻana i nā ʻauhau. nā mea maka, e ʻoluʻolu e hoʻokaʻaʻike mai iā mākou ma.
Ka manawa hoʻouna: Iune-14-2023