ʻO Paclitaxel, i ʻike ʻia he paclitaxel ʻulaʻula, tamsulosin, violet, a me tesu, ʻo ia ka lāʻau anti-cancer kūlohelohe maikaʻi loa i ʻike ʻia a hiki i kēia manawa, a ua hoʻohana nui ʻia i ka mālama ʻana i ka maʻi kanesa o ka umauma, ka maʻi kanesa ovarian, a me kekahi mau maʻi maʻi poʻo a me ka ʻāʻī. ka ma'i 'a'ai ma'i.Ma ke 'ano he lā'au lapa'au ma'amau o ka chemotherapy, ka inoa opaclitaxelUa manaʻo ʻia he nui ka poʻe i lohe.
ʻO ka ʻokoʻa ma waena o nā ʻano ʻehā opaclitaxel
1、Paclitaxel: Ke hana nei ia ma ka microtubule/microtubule protein system, inhibits microtubule depolymerization, blocks cell cycle in G2/M phase, alakaʻi i ka mitosis a i ʻole hopu ʻia, pale i ka hoʻopiʻi ʻana o nā cell tumor, a hiki ʻole i nā maʻi kanesa ke hoʻomau i ka māhele a make.
2、Docetaxel: Ua like ke ʻano o ka hana me ka paclitaxel, akā me ka pilina kiʻekiʻe i ka pūnaewele hoʻopaʻa microtubule a me ka hana anti-cancer kiʻekiʻe.
3、Liposomal paclitaxel: ʻO ke ʻano o ka hana e like me ka paclitaxel. ʻO nā liposomes i haku ʻia me ka lecithin, cholesterol, threonine a me nā mea ʻē aʻe e like me ka phospholipid bilayer structure o nā cell membranes encapsulate paclitaxel, hiki ke hoʻomaikaʻi i ka solubility wai, komo maʻalahi. i loko o nā ʻiʻo koko mai nā kīʻaha koko, a hoʻemi i ka ʻona o ka puʻuwai a me nā puʻupaʻa, etc.
4.Albumin-paclitaxel paclitaxel:hydrophobic paclitaxel ua hui pū me ke kanaka serum albumin carrier e nanotechnology.Albumin hiki ke hoʻonui i ka uptake o ka paclitaxel i ka maʻi maʻi ma o ka hoʻopaʻaʻana i ka gp60 receptor a hoʻonui i ka manaʻo o ka paclitaxel i loko o kaʻiʻo tumo, pēlā e hoʻonui ai i ka hopena anti-tumor. .
ʻO nā paclitaxel, doxorubicin, paclitaxel liposome a i ʻole albumin paclitaxel nā ʻano like o nā lāʻau chemotherapeutic, a aia nā mea āpau i ka papa paclitaxel i ka hoʻokaʻawale ʻana o nā lāʻau chemotherapeutic. ka mea hoʻopaneʻe, i hoʻohana nui ʻia i ka chemotherapy maʻi umauma.
'Ōlelo Aʻo: Loaʻa ka mana kūpono a me nā noi i uhi ʻia ma kēia hōʻikeʻike mai nā palapala i paʻi ʻia.
Heluhelu lōʻihi:Ke nānā nei ʻo Yunnan Hande Biotechnology Co., Ltd. i ka hana ʻana o ka paclitaxel no 28 mau makahiki.ʻO ia ka mea hana kūʻokoʻa mua o ka honua i ka paclitaxel lāʻau anticancer i loaʻa i ka mea kanu i ʻae ʻia e ka US FDA, European EDQM, Australian TGA, China CFDA, India, Iapana a me nā keʻena hoʻoponopono aupuni ʻē aʻe.ʻoihana.Inā makemake ʻoe e kūʻaiAPI Paclitaxel, e ʻoluʻolu e kelepona mai iā mākou ma ka pūnaewele.
Ka manawa kau: Oct-08-2022