ʻO ka lau Mulberry DNJ ʻo ka lau Mulberry ka mea ola kino

Nā ʻike huahana

ʻO ka lau Mulberry DNJ he alkaloid maoli, nona ka inoa Kina he 1-deoxynojirimycin.He potent glucose metabolizing enzyme (eg α-Glycosidase) inhibitor hiki ke hoʻopaneʻe nui i ke kaʻina hana degradation o polysaccharide, hoʻemi i ka waiwai kiʻekiʻe o ka glucose koko postprandial a hoʻopaʻa i ka glucose koko hoʻokēʻai;Aia ia i ka "inhibitory factor" ma waena o nā kumu hoʻomalu kō ʻehā o ka alfa.
1、 Ka hopena o ka lau mulberry DNJ
1. Alanui ʻekolu e hoʻemi i ka glucose koko
Ma ke ʻano he mea paʻa ikaika o ka glucose metabolizing enzymes (eg α-Glucosidase, hexokinase, glucuronidase a me glycogen phosphatase, etc.), hiki i ka DNJ ke hoʻopaneʻe nui i ke kaʻina hana degradation o polysaccharide, hoʻemi i ka waiwai kiʻekiʻe o ka glucose koko postprandial a hoʻopaʻa i ka glucose koko hoʻokēʻai.Eia kekahi, loaʻa iā DNJ ka hopena o ka ʻike ʻana i ka insulin e hoʻomaikaʻi ai i ka pale ʻana o ka insulin.
2. E hoemi i ke koko koko postprandial.
ʻO ka α- Glucosidase ka mea i puʻunaue nui ʻia i loko o ka ʻōpū liʻiliʻi o ke kanaka a he hana koʻikoʻi i ka decomposition o nā carbohydrates.ʻO lākou ke kuleana no ka decomposition o nā oligosaccharides e like me ka oligosaccharides i ka meaʻai i loko o nā monosaccharides, e like me ka glucose.Hoʻokomo kēia mau glucose i ke kino ma o ka paia o ka ʻōpū, e piʻi nui ana i ka pae koko.He kūlohelohe a ikaika ka DNJ α- Glucosidase inhibitors e hoʻopaʻa i ka hoʻokūkū i loko o ka ʻōpū liʻiliʻi α- ʻOi aku ka kiʻekiʻe o ka pili o ka glucosidase ma mua o ka oligosaccharides e like me ka sucrose a me ka maltose α- He pili ikaika ka Glucosidase a hoʻemi i ka oligosaccharides a me ka α- ʻO ka hiki ke hoʻopaʻa ʻia ka glucosidase. , i mea e pale ai i ka decomposition o ka fructose i ka glucose, a ʻaʻole e komo ka nui o ke kō a hoʻouna ʻia i ka ʻōpū nui.Ma muli o ka hopena o DNJ, emi iho ka glucose i loko o ke koko, no laila pono ke mālama ʻia ka glucose koko ma kahi pae olakino.
3. Paʻa ka hoʻokē ʻai koko glucose.
Loaʻa i ka DNJ ka hana pale o ka glycogen phosphorylase, hiki ke hoʻolohi i ka hoʻohaʻahaʻa ʻana o ka glycogen ate i ka glucose, i mea e hoʻopaʻa ai i ka glucose koko hoʻokēʻai.ʻO ka glucose "ʻoi aku" i loko o ke kino kanaka e mālama ʻia i loko o ke ake ma ke ʻano o ka glycogen.Hiki ke wāwahi ʻia ka glycogen i ka glucose ma lalo o ka hana a ka glycogen phosphorylase a hoʻokuʻu ʻia i loko o ke koko e hoʻokō i nā pono o ka ʻiʻo a me nā hana ʻē aʻe.ʻO Glycogen kekahi o nā kumu ikehu nui no ka hana kino.Me ka hoʻololi like ʻana ma waena o ka glycogen a me ka glucose, ʻo ka glucose koko o ka poʻe maʻamau i ke kaulike ikaika.I nā poʻe maʻi maʻi maʻi, ma muli o ka hana ʻole o ka metabolism glucose, ʻoi aku ka nui o ka glycogen e wāwahi i ka glucose, e hopena i ka piʻi ʻana o ka glucose koko hoʻokēʻai.Hiki i ka DNJ ke pale i ka hana o ka glycogen phosphorylase a pale i ka piʻi ʻana o ka glucose koko ma muli o ka hoʻoheheʻe ʻana o ka glycogen i ka glucose, i mea e hoʻopaʻa ai i ka glucose koko hoʻokēʻai.
4. E hoʻomaikaʻi i ka insulin resistance.
Hiki i ka DNJ ke hoʻomaikaʻi i nā hōʻailona o ka pale ʻana o ka insulin ma o ka hoʻoponopono ʻana i ka metabolism lipid, hoʻolohi i ka hana glucose a me ka ʻike insulin.ʻO ke kūpaʻa ʻana o ka insulin e pili ana i nā kumu like ʻole (ʻo ia hoʻi me nā kumu genetic a me ka momona), ka mea e hōʻemi ai i ka pono o ka insulin e hoʻoikaika ana i ka lawe ʻana a me ka hoʻohana ʻana i ka glucose, a hūnā ke kino i ka nui o ka insulin.ʻO ke kū'ēʻana o ka insulin e hoʻopuka i ka hyperinsulinemia e mālama i ka paʻa o ke koko glucose i loko o ke kino.Inā lōʻihi ke kino o ke kanaka i ka insulin resistance, e hoʻonui nui ia i ke kaumaha o ka pancreas.Hiki iā ia ke hana i ka pancreas e hūnā i ka hemahema o ka hana o ka insulin a laila e ulu aʻe i ka maʻi diabetes.Hiki i ka DNJ ke hoʻomaikaʻi i nā hōʻailona o ka pale ʻana o ka insulin ma o ka mālama ʻana i ka glucose koko olakino, hoʻoponopono i ka metabolism lipid a me ka hoʻonui ʻana i ka ʻike insulin.
2、 Nā kahua noi o ka lau mulberry DNJ
Ua helu ʻia ka lau Mulberry leaf DNJ ma ke ʻano he hopena hypoglycemic kōkua a hoʻohana nui ʻia i ka meaʻai olakino.

Nā Kūlana Huahana

KULA HANA
inoa mea kūʻai	ʻO ka lau Mulberry DNJ
CAS	19130-96-2
ʻO ke kimekema	C6H13NO4
Brand	Hʻo ʻaneʻi
Mmea hana	Yunnan Hande Bio-Tech Co., Ltd.
Cʻāina	Kunming,China
Hoʻokumu ʻia	1993
BʻIkepili ASIC
Nā huaʻōlelo like	(2r,3r,4r,5s)-2-hydroxymethyl-3,4,5-trihydroxypiperidine;5-piperidinetriol,2-(hydroxymethyl)-,(2r-(2alpha,3beta,4alpha,5beta))-4;bay-h5595;moranolin;moranoline; (+)-1-DEOXYNOJIRIMYCIN;1-DEOXYNOJIRIMYCIN;(2R,3R,4R,5S)-2-(HYDROXYMETHYL)-3,4,5-PIPERIDINETRIOL
Kapili
Kaumaha	N/A
HS Code	N/A
ʻAno maikaʻiShoʻopaʻapaʻa	Hōʻikeʻike Hui
Cpalapala hōʻoia	N/A
Hoʻāʻo	Hoʻopilikino ʻia e like me nā pono o ka mea kūʻai aku
Ka nana aku	Pauda keʻokeʻo
ʻano o ka unuhi ʻana	Wehe ʻia mai nā lau mulberry a me ka ʻili aʻa
Makahiki Makahiki	Hoʻopilikino ʻia e like me nā pono o ka mea kūʻai aku
Pūʻolo	Hoʻopilikino ʻia e like me nā pono o ka mea kūʻai aku
Hana Hoao	HPLC
Loko	lehulehuhalihalis
PhāʻawiTerms	T/T, D/P, D/A
Other	E ʻae i ka loiloi mea kūʻai aku i nā manawa a pau;E kōkua i nā mea kūʻai aku me ka hoʻopaʻa inoa hoʻoponopono.

1. ʻO nā huahana a pau i kūʻai ʻia e ka ʻoihana he semi-finished maka.Kuhi nui ʻia nā huahana i nā mea hana me nā hōʻailona hana, a ʻaʻole nā ​​​​mea waiwai nā huahana hope loa.
2. ʻO ka pono kūpono a me nā noi i komo i ka hoʻolauna mai nā palapala i paʻi ʻia.ʻAʻole ʻōlelo ka poʻe i ka hoʻohana pololei ʻana, a hōʻole ʻia nā kūʻai kūʻai.
3. ʻO nā kiʻi a me nā ʻike huahana ma kēia pūnaewele no ka kuhikuhi wale nō, a e lanakila ka huahana maoli.