ʻO ka Semi-synthetic paclitaxel kahi lāʻau anticancer i hoʻohana nui ʻia i ka hoʻomaʻamaʻa lapaʻau, i hoʻohana nui ʻia i ka mālama ʻana i nā maʻi maʻi like ʻole ma muli o kona maikaʻi kupaianaha a me nā hopena ʻona haʻahaʻa haʻahaʻa. hana a me ka hoʻohana lapaʻau opaclitaxel semi-synthetickikoʻī.
Mechanism o ka hana
ʻO ke ʻano hana o kapaclitaxel semi-syntheticʻO ka mea nui ma o ke kāohi ʻana i ka polymerization o ka tubulin, ka luku ʻana i ka pūnaewele microtubule cell, no laila ke kāohi nei i ka hoʻonui ʻana o ka cell a me ka hoʻoulu ʻana i ka apoptosis cell. .
Nā hopena lāʻau lapaʻau
Ua hōʻike ʻo Semi-synthetic paclitaxel i ka hana anticancer kupaianaha i nā hoʻokolohua pharmacological, a he hopena therapeutic maikaʻi i nā maʻi maʻi like ʻole e like me ka maʻi kanesa o ka umauma, ka maʻi ʻaʻai ovarian a me ka maʻi maʻi ʻāʻī.
Kāohi ʻana i ka hoʻonui ʻana o ke kelepona: hiki i ka paclitaxel semi-synthetic ke kāohi i ka hoʻonui ʻana o nā pūnaewele tumo, ʻoi aku hoʻi no nā cell i ka pae mitotic.
Ka hoʻokomo ʻana o ka apoptosis: hiki i ka semi-synthetic paclitaxel ke hoʻoulu i ka apoptosis o nā pūnaewele maʻi ma o ka hoʻoponopono ʻana i ke ʻano o ka apoptosis o nā pūnaewele tumo, i mea e hoʻokō ai i ke kumu o ka mālama ʻana i ka maʻi maʻi.
E hoʻonui i ka pane kūlohelohe: hiki i ka paclitaxel semi-synthetic ke hoʻoponopono i ka pane ʻana o nā cell tumor a hoʻonui i ka hiki ke anti-tumor o ke kino.
Hoʻohana lapaʻau
Hoʻohana nui ʻia ka paclitaxel semi-synthetic i ka mālama ʻana i nā maʻi maʻi like ʻole, e like me ka maʻi kanesa o ka umauma, ka maʻi ʻaʻai ovarian, ka maʻi ʻaʻai māmā a pēlā aku. ʻO nā maʻi maʻi like ʻole. I ka hoʻohana ʻana i ka lāʻau lapaʻau, hoʻohana pinepine ʻia ka paclitaxel semi-synthetic i hui pū ʻia me nā mea hana chemotherapeutic ʻē aʻe e hoʻomaikaʻi ai i ka hopena therapeutic.
Nā hopena ʻino
He haʻahaʻa loa nā hopena ʻino o ka paclitaxel semi-synthetic, akā hiki ke hoʻoulu i kekahi mau hopena maikaʻi ʻole, e like me ka anaphylaxis, ka hoʻopau ʻana i ka iwi iwi, ka ʻona o ka naʻau, a me nā mea ʻē aʻe. e like me ke kūlana kūikawā o ka mea maʻi a me ka hoʻomanawanui o ka lāʻau lapaʻau e hōʻemi i ka hopena o nā hopena ʻino i ka mea maʻi.
Nā Manaʻo hoʻomohala e hiki mai ana
Me ka holomua mau o ka ʻepekema a me ka ʻenehana a me ka hohonu o ka noiʻi ʻana ma ka paclitaxel, e ʻoi aku ka nui a me ka hohonu o ka noiʻi e hiki mai ana ma ka paclitaxel semi-synthetic. E alakaʻi ʻia ka noiʻi e pili ana i ka hoʻomaikaʻi ʻana i ka hopena therapeutic o ka paclitaxel semi-synthetic a hōʻemi i kāna mau hopena ʻino. hiki nō hoʻi, e hāʻawi ana i nā maʻi maʻi maʻi i nā koho lapaʻau kūpono a maikaʻi hoʻi.
Ka hopena
Ma ke ʻano he lāʻau anticancer koʻikoʻi,paclitaxel semi-syntheticLoaʻa ka laulā o nā noi lapaʻau. ʻO kona hopena therapeutic koʻikoʻi a me nā hopena ʻona haʻahaʻa haʻahaʻa e lilo ia i hoʻokahi o nā koho nui no ka mālama ʻana i nā maʻi maʻi he nui. maikaʻi loa, e hāʻawi ana i nā ala lapaʻau maikaʻi a me nā manaʻolana ola no nā maʻi maʻi maʻi.
'Ōlelo Aʻo: Loaʻa nā pōmaikaʻi a me nā noi i hōʻike ʻia ma kēia ʻatikala mai nā palapala i paʻi ʻia.
Ka manawa hoʻouna: Nov-28-2023