He aha nā mea maikaʻi o ka paclitaxel polymer micelles?

Ua ʻike mākou ʻo nā ʻano o ka paclitaxel i kūʻai ʻia ʻo ia ka paclitaxel injection, liposomal paclitaxel, docetaxel, a me albumin-bound paclitaxel.He aha nā mea maikaʻi o ka paclitaxel hou a me ka paclitaxel polymer micelles?E nānā kākou i kēia mau mea.

ʻO nā pono o ka paclitaxel polymer micelles

1. Hoʻohui ʻia ka copolymer i loko o ka wai e hana i kahi nanocarrier me kahi ʻano "core-shell".ʻAʻole hoʻohaʻahaʻa ʻia ka paclitaxel i hoʻopaʻa ʻia i ka nuklea o ka micelle, i hiki iā ia ke pāʻani i ke ʻano o ke koko no ka manawa lōʻihi.

2. He liʻiliʻi loa ka polymer micellar paclitaxel particles (18-20nm), hiki ke hoʻopaʻa ʻia i loko o ka microenvironment tumor me nā maʻi vascular.Ma kēia ala, ʻoi aku ka maikaʻi o ka lāʻau lapaʻau e noho i loko o ka ʻiʻo tumo, e hopena i kona kiʻekiʻe kiʻekiʻe i loko o ka ʻiʻo maʻi a me ka haʻahaʻa haʻahaʻa i ka ʻiʻo maʻamau.ʻOiai e hoʻomaikaʻi ana i ka pono, ua hoʻemi hou ʻia ka hopena o nā hopena ʻaoʻao.

Hoʻohana i nā micelles polymer paclitaxel ma Kina

I ʻOkakopa 2021, ua hoʻolaha ʻo China National Drug Administration (NMPA) ua ʻae ʻia ka paclitaxel polymer micelle mua ma Kina, a ʻo ka hōʻailona ʻo ia ka maʻi maʻi ʻaʻai liʻiliʻi liʻiliʻi.

'Ōlelo Aʻo: ʻO ka pono a me nā noi i hoʻokomo ʻia ma kēia ʻatikala mai nā palapala i paʻi ʻia.

ʻO Yunnan Hande Biotechnology Co., Ltd ua loea i ka hana ʻana oAPI paclitaxelno nā makahiki ʻoi aku ma mua o 20, a ʻo ia kekahi o nā mea hana kūʻokoʻa o ka honua i ka paclitaxel API, kahi lāʻau anti-cancer i loaʻa i nā mea kanu, i ʻae ʻia e ka US FDA, European EDQM, Australian TGA, Chinese CFDA, India, Iapana a me nā keʻena hoʻoponopono aupuni ʻē aʻe. .Hiki i ka Hande ke hāʻawi i ka mea kiʻekiʻe wale nōpaclitaxel maka, akā, ʻo nā lawelawe hoʻomaikaʻi ʻenehana e pili ana i ka hana paclitaxel.No ka ʻike hou aku, e ʻoluʻolu e kelepona mai iā mākou ma 18187887160.