He aha ka paclitaxel, paclitaxel no ka hoʻokuʻu ʻia ʻana a me ka paclitaxel paʻa albumin? He aha nā mea hoʻohana nui? E wehewehe pōkole mākou iā lākou ma kēia ʻatikala.
Hiki i kahi metabolite lua maoli i hoʻokaʻawale ʻia a hoʻomaʻemaʻe ʻia mai ka ʻili, nā lālā a me nā lau o ka gymnospermous taxus chinensis hiki ke hoʻoikaika i ka polymerization microtubule a hoʻopaʻa i nā microtubules polymerized. me nā hana like ʻole o nā cell, ʻoi aku ka hoʻopau ʻana i ka māhele cell ma ka mitotic stage, a poloka i ka mahele cell maʻamau.
Loaʻa iā ia ka hopena anti-tumor maikaʻi a hoʻohana ʻia no ka mālama ʻana i ka maʻi maʻi umauma holomua, ka maʻi maʻi ʻōpū, ka maʻi maʻi ovarian, ka maʻi maʻi poʻo a me ka ʻāʻī, ka maʻi maʻi ʻiʻo palupalu a me ka maʻi maʻi digestive.
ʻO Paclitaxel (Taxol) kahi API anticancer (Active Pharmaceutical Ingredient), ʻaʻole hiki ke hoʻohana pololei ʻia e nā kānaka.
I kēia manawa, ʻo ka paclitaxel i hoʻohana nui ʻia he anticancer injections a me nā mea lapaʻau (me nā stents a me nā baluna). Hoʻomaikaʻi mau. Manaʻo ʻia i ka wā e hiki mai ana, e ʻoi aku ka palekana a ʻoi aku ka maikaʻi o ka mālama ʻana i nā kauka a me nā maʻi, a ʻoi aku ka nui o nā ʻano lāʻau anticancer i loaʻa ka paclitaxel me ka hopena anticancer ikaika.
ʻO Paclitaxel no ka hoʻokuʻu ʻia ʻana:
ʻO kahi injection i loaʻa i ka paclitaxel API.
Hoʻokomo pū ʻia ʻo Paclitaxel no ka ʻinikua polyoxyethylene castor oil paclitaxel injection; Liposome paclitaxel injection; Albumin bound paclitaxel injection; Micellar paclitaxel a me nā ʻano hana ʻē aʻe.
Hoʻohana nui ʻia ia i ka maʻi maʻi umauma, ka maʻi kanesa, ka maʻi maʻi ovarian a me nā maʻi ʻē aʻe, a ʻo ia kekahi o nā lāʻau anticancer maikaʻi loa i kēia manawa.
Paclitaxel paʻa i ka Albumin:
ʻO ka paclitaxel i hoʻopaʻa ʻia i ka albumin he mea hoʻomākaukau e hui pū ana i ka paclitaxel a me albumin. No ka paclitaxel no ka injection a ʻo ia kekahi o nā injections paclitaxel i hoʻohana nui ʻia me ka palekana kiʻekiʻe.
ʻO Albumin paclitaxel, ka mea mua i komo i ka maka o ka poʻe ʻo ABRAXANE Injection (ABRAXANE For Injectable Suspension paclitaxel protein-bound particles for injectable suspension, album-bound) i ʻāpono ʻia e FDA i ka makahiki 2005, i hoʻohana ʻia e mālama i ka maʻi maʻi umauma metastatic. ʻO ka hoʻopau hou ʻana ma kahi o 130 nm, ʻaʻole ia i loko o nā mea ʻawaʻawa. nā ʻoihana lāʻau lapaʻau nui i ka wā e hiki mai ana.
Hoʻohana nui ia i ka mālama ʻana i ka maʻi maʻi umauma metastatic i hāʻule ʻole i ka chemotherapy hui a i ʻole ka maʻi maʻi umauma e hoʻi hou i loko o 6 mau mahina ma hope o ka adjuvant chemotherapy.
Ua kūpaʻa ʻo Yunnan Hande Bio-Tech i ka noiʻi a me ka hoʻomohala ʻana a me ka hana ʻana opaclitaxel,docetaxel,10-DAB semi-synthetic paclitaxel,acabazitaxel, a he noiʻi ʻikepili kikoʻī e pili ana i nā haumia like ʻole i loko o ka paclitaxel. Eia kekahi, hāʻawi pū ʻo Hande i nā lawelawe hoʻololi ʻenehana e pili ana i ka paclitaxel: nā injections paclitaxel kuʻuna; Albumin bound paclitaxel injections etc. 18187887160）
Ka manawa hoʻouna: Feb-09-2023