ʻOihana Hoʻololi ʻenehana no nā ʻano hana Paclitaxel maʻamau

ʻOihana Hoʻololi ʻenehana no nā Kiʻi Kūlana Paclitaxel

ʻO ka wehewehe pōkole:

ʻO Paclitaxel kahi lāʻau anti-tumor i hoʻohana nui ʻia. ʻO ka paclitaxel injection i hoʻohana ʻia i kēia manawa i ka hoʻomaʻamaʻa lapaʻau e hoʻohana ana i ka ʻaila castor polyoxyethylene e like me ka solubilizer, akā kiʻekiʻe ka hopena o nā hopena ʻino i ka wā o ka hoʻohana ʻana i ka lāʻau lapaʻau, no laila pono ka mea maʻi e hana i ka lāʻau anti allergy ma mua o ka lawelawe ʻana, ka mea e lawe mai ai i na pilikia he nui i na ma'i a me na kauka. I mea e hoopau ai i na hopena ino i hanaia e ka aila castor polyoxyethyl, e lanakila i na hemahema o na hoomakaukau ana e noho nei, a e hoonui i ka solubility a me ka pa'a o ka paclitaxel, ua komo mai ka paclitaxel pa'a Albumin. ʻO ka lawelawe hoʻoili no nā ʻano hoʻohālikelike ʻo Paclitaxel maʻamau. No ka ʻike hou aku, e ʻoluʻolu e nīnau ma ka pūnaewele.

E hoʻouna i ka leka uila iā mākou

Huahana Huahana

Paclitaxel

Hiki i kahi metabolite lua maoli i hoʻokaʻawale ʻia a hoʻomaʻemaʻe ʻia mai ka ʻili, nā lālā a me nā lau o ka gymnospermous taxus chinensis hiki ke hoʻoikaika i ka polymerization microtubule a hoʻopaʻa i nā microtubules polymerized.ʻO nā pūnaewele i hōʻike ʻia i ka paclitaxel e hōʻiliʻili i ka nui o nā microtubules i loko o nā keena.ʻO ka hōʻiliʻili ʻana o kēia mau microtubules e hoʻopilikia i nā hana like ʻole o nā pūnaewele, ʻoi aku ka hoʻōki ʻana i ka māhele cell ma ka mitotic stage, a poloka i ka mahele cell maʻamau.

I kēia manawa, ʻo ka paclitaxel i hoʻohana nui ʻia ʻo ia ka anticancer injections a me nā mea lapaʻau (me nā stents a me nā baluna).Me ka hoʻomohala wikiwiki ʻana o ka biotechnology a me ka ʻenehana lapaʻau, e ʻimi mau ʻia ka hoʻohana ʻana i ka paclitaxel, a ke hoʻomaikaʻi mau ʻia nā kūlana like ʻole o nā maʻi.E manaʻoʻiʻo i ka wā e hiki mai ana, e ʻoi aku ka palekana a me ka maikaʻi o ka mālama ʻana i nā kauka a me nā maʻi, a ʻoi aku ka nui o nā ʻano lāʻau anticancer i loaʻa ka paclitaxel me ka hopena anticancer ikaika.

Holomua papahana

Ua pau ka haʻawina preclinical a ua oʻo ka papa hana hoʻomākaukau.